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Venn rejuvenative dropper bottle on a white background
  • Venn rejuvenative dropper bottle on a white background
  • VENN Rejuvenative PDRN-NE Ampoule
  • VENN Rejuvenative PDRN-NE Ampoule
  • VENN Rejuvenative PDRN-NE Ampoule
  • Venn rejuvenative dropper bottle on a white background
  • VENN Rejuvenative PDRN-NE Ampoule
  • VENN Rejuvenative PDRN-NE Ampoule
  • VENN Rejuvenative PDRN-NE Ampoule
VENN Rejuvenative PDRN-NE Ampoule
$413.00

THE NEXT ERA IN CELLULAR SKINCARE: Nano-Emulsion advanced delivery for visible revitalization. 

Rejuvenative PDRN-NE Ampoule face serum is a high-performance skin-conditioning program featuring 1% intact salmon-derived PDRN delivered through a proprietary nano-emulsion delivery system to visibly lift, firm, smooth, and refine the complexion. Each set includes four 5ml vials, providing a 4-week intensive skin rejuvenation program.

Best for: This advanced serum-emulsion absorbs softly into the skin while providing a comforting veil of moisture - ideal for dry, mature, depleted or fatigued-looking skin in need of visible revitalization and support. With noticeable improvements in the appearance of elasticity and suppleness, it delivers a visibly refined skin texture with enhanced comfort and firmness-looking results. 

Volume: 5ml x 4ea

Rejuvenative PDRN-NE Ampoule (5ml x 4ea) is a four-week, intensive skin-conditioning program powered by intact Sodium DNA (PDRN) at a clinically optimized 1% concentration. Each set includes four 5ml vials, designed for weekly use to help improve the appearance of skin elasticity, firmness, tone, and smoothness, leaving the complexion looking more refined and revitalized.

The challenge with PDRN is its size. By definition, Sodium DNA (PDRN) is a very large molecule, making it extremely difficult to pass through the skin barrier with standard topical application. To address this, many products use hydrolyzed Sodium DNA—DNA broken into smaller fragments that may absorb more easily but lose the unique skin benefits of true PDRN.

VENN solution is different: VENN preserve intact PDRN in its biologically active form and deliver it with an advanced nanoemulsion (NE) system. These ultra-fine, sub-200 nm droplets:

  • Protect PDRN until it reaches the skin
  • Enhance absorption and even dispersion for optimal performance on the skin.

The result is a topical treatment that better preserves the efficacy of PDRN. 

VENN Technology & Innovation 

Advanced Nanoemulsion Delivery (NE)
  • Effective Delivery: Sub-200 nm droplets ensure effective delivery and even dispersion for optimal cosmetic performance on the skin.
  • Molecular Integrity: PDRN is kept intact (not pre-hydrolyzed) and then naturally broken down and released in the skin to visibly refine and revitalize the skin’s complexion.
  • Stability & Controlled Release: Encapsulation protects PDRN and enables a sustained release of actives.
  • Blue Hue: The faint opalescent tint is a natural Tyndall effect, confirming nanoscale
    dispersion.
Why VENN System Outperforms Hydrolyzed DNA
  • Active Integrity: Uses intact Sodium DNA (PDRN), not fragmented hydrolyzed DNA.
  • Mechanism: Intact PDRN retains the ability to visibly revitalize the skin’s complexion; hydrolyzed DNA primarily functions as a humectant.
  • Delivery: Nanoemulsion enhances penetration and gradual release; hydrolyzed forms rely on passive absorption only.
  • Bioavailability: Encapsulation improves stability and visible results.
  • Visual Cue: Translucent, faint blue appearance confirms true nanocolloidal state

Clinically Tested. Dermatologist tested. Cruelty free and Leaping Bunny Certified.
Key Natural Actives

VENN PDRN ORIGIN
VENN PDRN is sourced from highly purified salmon sperm DNA, chosen for its exceptional purity, structural similarity to human DNA, and ability to remain intact for optimal performance.

While many formulas rely on hydrolyzed or plant-derived DNA fragments—which mainly act as humectants—VENN use of intact, long-chain PDRN preserves the molecule’s natural integrity and enables superior performance when paired with the VENN nano-emulsion delivery system.

PRIMARY ACTIVES

  • Sodium DNA (PDRN): High-molecular-weight DNA fragments
    valued for helping improve the appearance of skin elasticity, firmness, and overall skin vitality.
  • Advanced Nanoemulsion Carrier (sub 200 nm): Translucent, kinetically stable droplets that protect and deliver PDRN.
  • Peptide Complex: sh-Oligopeptide-1 (10 ppm EGF), Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
    for smoother, firmer-looking skin.
  • 5% Croderm P (Encapsulated Panthenol): Advanced delivery of
    Pro-Vitamin B5 for intensive soothing and hydration.

SUPPORTING ACTIVES

  • Hydration Network: Sodium Hyaluronate, Hydroxyethyl Urea, Glyceryl Glucoside, Betaine for multi-layer hydration.
  • Ectoin & Ceramide NP: Help reinforce the moisture barrier and improve resilience.
  • Glutathione & 17 Amino Acids (Glycine, Carnosine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine)
Ritual
  • Use morning and night. Apply one 5 ml ampoule per week to complete the full 4-week program.
  • Dispense 6–9 drops into your palm and gently pat onto clean, dry skin (face and neck) until fully absorbed.
  • Follow with your preferred moisturizer to lock in hydration.

The program can be repeated every 2–3 months, or used daily as a continuous serum treatment.

PDRN VS. EXOSOME: WHEN TO USE EACH
Both ampoules are designed to help improve the appearance of skin quality, while addressing different skin concerns through distinct formulation approaches.

Rejuvenative PDRN-NE Ampoule is formulated to help enhance the appearance of skin comfort, resilience, and smoothness. It helps visibly refine skin texture and support a well-conditioned, moisturized look, with noticeable improvements in the appearance of elasticity and suppleness. Its richer emulsion texture makes it especially well-suited for dry, mature, depleted, or fatigued-looking skin in need of enhanced comfort and firmness-looking results.

Regenerative 10B-EXO EGF Ampoule is formulated to help improve the appearance of skin texture, elasticity, and tone while promoting a calm, balanced-looking complexion. Its lightweight, fast-absorbing texture makes it an excellent option for combination, stressed, sensitive-looking, or post-procedure skin, helping skin appear smoother, clearer, and more refined.

Caution: For topical, external use only. Do not use in case of allergy to any of the ingredients. Discontinue use if signs of irritation or rash appear and consult a doctor. Avoid direct contact with eyes. Store in a cool and dry place, away from direct sunlight and heat, out of the reach of children.
Clinical Testing
Clinically Tested: visible benefits in just 2 weeks*
  • Visibly enhanced surface and deep skin elasticity
  • Visible lifting effect around cheeks, chin, nasolabial folds, and mouth corners
  • Reduced the appearance of wrinkles
  • Visibly reduced the appearance of redness
  • Visibly reduced superficial dark spots and hyperpigmentation
  • Improved the look of deep pigmentation and dark spots
*based on in-vivo clinical tests on 20 subjects over 2 weeks

Consumer perception study results (20 subjects / after 2 weeks of use, morning and evening):

  • 100% agreed their skin felt more elastic.
  • 100% agreed their skin appeared lifted.
  • 100% agreed their skin felt soothed.
  • 100% agreed their skin looked healthier and younger.
  • 100% agreed their overall skin condition improved.
  • 100% agreed their skin tone improved.
  • 100% agreed their skin tone appeared more even.
  • 100% agreed their pores appeared smaller.
  • 100% agreed their skin looked brighter.
  • 95% agreed the appearance of wrinkles around the eyes was reduced
*Manufacturer's claims.
Ingredients

VENN STANDARDS

  • Dermatologist tested for safety: Non irritating. Non sensitizing.
  • Formulated without fragrance, parabens, silicones, phthalates, mineral oil, colorants, sulfates (SLS/SLES), PEG compounds, phenoxyethanol, coal tar, and other controversial ingredients that we believe can be toxic and unsafe for the skin.
  • Cruelty free. Leaping Bunny certified.

FULL INREDIENT LIST: Water, Propanediol, Butylene Glycol, Glycerin, C13 15 Alkane, Polyglyceryl 10 Oleate, HydroxyethylUrea, Glyceryl Glucoside, Sodium DNA, Methylpropanediol, Sodium Hyaluronate, Ectoin, CeramideNP, Glutathione, Glycine, Carnosine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine,Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine,Cysteine, Betaine, sh Oligopeptide 1, Acetyl Hexapeptide 8, Palmitoyl Tetrapeptide 7, PalmitoylTripeptide 1, Dipropylene Glycol, 1,2 Hexanediol, Sodium Polyacryloyldimethyl Taurate, Squalane,Simmondsia Chinensis (Jojoba) Seed Oil, Trehalose, Panthenol, Hydrogenated Lecithin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Cetearyl Olivate, Sorbitan Olivate, Tetrasodium Glutamate Diacetate, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Scutellaria Baicalensis Root Extract, Sorbitan Isostearate, Nephelium Lappaceum Peel Extract, Helianthus Annuus (Sunflower) Seed Oil, Dipotassium Glycyrrhizate, Illicium Verum (Anise) Fruit Extract, Ethylhexylglycerin, Adenosine, Citric Acid, Beta Glucan, Cyclodextrin.

Made in South Korea

At The NATIVES Co. we do our best to provide you with accurate and up-to-date product information and ingredients. However, this may be subject to change at the manufacturer’s discretion. Please refer to the product packaging for final ingredient information.
Country of Origin
  • South Korea
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